Just keep in mind the CGT implications.

When you sell your primary residence you will get a primary residence exclusion from CGT. You are now earning income on a portion of the house and thus that portion does not fall under the primary residence exclusion.

So when you sell the property you will have to calculate what part of the property was used for generating income and what part was your primary residence portion. Your primary residence portion will qualify for the primary residence exclusion, but the business portion will not