I got this too - was working fine on Sunday, and Monday the problem occurred. What I did eventually (I am still using Windows XP) was to go to C:\Documents and settings\(your user name)\application data (which is a hidden file)\ and found a folder called "easyfileemployer.(many numbers and letters). I deleted the whole folder (hoping that I could restore it from the recycle bin if necessary) and restarted e@syfile. It asked me to enter my password as if for the first time, and then opened up for me. I restored from my backup and was able to work on it again. Hope this helps.
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